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SELANK 10MG

SELANK 10MG

$45.00

Selank Selank is a synthetic heptapeptide analog of tuftsin (Thr-Lys-Pro-Arg) with a C-terminal Pro-Gly-Pro extension. Preclinical studies in cell cultures and animal models indicate that Selank modulates GABAergic neurotransmission, exhibits anxiolytic-like effects, and supports cognitive function without sedation or significant side effects on motor activity.[1][2] Key Research Areas Anxiolytic & Stress-Protective Effects – In rodent…

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Selank

Selank is a synthetic heptapeptide analog of tuftsin (Thr-Lys-Pro-Arg) with a C-terminal Pro-Gly-Pro extension. Preclinical studies in cell cultures and animal models indicate that Selank modulates GABAergic neurotransmission, exhibits anxiolytic-like effects, and supports cognitive function without sedation or significant side effects on motor activity.[1][2]

Key Research Areas

  • Anxiolytic & Stress-Protective Effects – In rodent models of acute and chronic stress, Selank has been shown to reduce anxiety-like behaviors in elevated plus-maze and open-field tests, normalize stress-induced changes in serotonin and enkephalin levels, and protect against emotional stress responses.[3][4]
  • Cognitive Enhancement & Memory Processes – Preclinical investigations demonstrate Selank improves learning and memory consolidation in models of impaired cognition (e.g., induced by stress or scopolamine), enhances attention, and modulates brain-derived neurotrophic factor (BDNF) expression.[5][6]
  • Neuroprotective & Anti-Inflammatory Pathways – Animal studies suggest Selank influences enkephalinase activity, reduces pro-inflammatory cytokine release, and supports neuronal survival under oxidative stress or inflammatory conditions.[7][8]

Product Specifications

CAS Number 129954-34-3
Molecular Formula C33H57N11O9
Molar Mass 751.89 g/mol
Sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro
Synonyms Selank, TP-7, Selanc (brand in some regions)
Purity ≥99% (HPLC)
Form Lyophilized powder
Storage −20°C (long-term), 2–8°C (reconstituted)
Solubility Bacteriostatic water or sterile saline for reconstitution

References

  1. 1. Ashmarin IP, et al. Design and study of a new class of peptide bioregulators. Bull Exp Biol Med. 2002. PubMed
  2. 2. Zozulya AA, et al. The inhibitory effect of Selank on the development of anxiety in rats. Neurosci Behav Physiol. 2008. PubMed
  3. 3. Volkova A, et al. Selank normalizes parameters of the incretin system in rats with experimental diabetes mellitus. Bull Exp Biol Med. 2016. PubMed
  4. 4. Kozlovskaya II, et al. The anxiolytic effect of Selank in experimental models of anxiety. Zh Nevrol Psikhiatr Im S S Korsakova. 2002. (Anxiolytic data)
  5. 5. Medvedev VE, et al. Selank in the therapy of generalized anxiety disorder and neurasthenia. Zh Nevrol Psikhiatr Im S S Korsakova. 2006. (Cognitive context)
  6. 6. Inozemtseva LS, et al. Selank restores memory in rats with impaired learning. Bull Exp Biol Med. 2007. PubMed
  7. 7. Kolomin TA, et al. Selank modulates enkephalinase activity in the brain. Bull Exp Biol Med. 2010. PubMed
  8. 8. Zozulya AA, et al. Selank in experimental models of inflammation. Bull Exp Biol Med. 2009. (Anti-inflammatory data)
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