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SLU-PP-332 250MCG - 60CT

SLU-PP-332 250MCG – 60CT

$99.00

SLU-PP-332 CAPSULES 250MCG – 60CT SLU-PP-332 is a synthetic small molecule pan-ERR (estrogen-related receptor) agonist. Preclinical studies in cell cultures and animal models indicate that SLU-PP-332 activates ERRα, ERRβ, and ERRγ, mimicking some metabolic effects of exercise by upregulating mitochondrial biogenesis, fatty acid oxidation, and oxidative phosphorylation in skeletal muscle and other tissues.[1][2] Key Research…

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SLU-PP-332 CAPSULES 250MCG – 60CT

SLU-PP-332 is a synthetic small molecule pan-ERR (estrogen-related receptor) agonist. Preclinical studies in cell cultures and animal models indicate that SLU-PP-332 activates ERRα, ERRβ, and ERRγ, mimicking some metabolic effects of exercise by upregulating mitochondrial biogenesis, fatty acid oxidation, and oxidative phosphorylation in skeletal muscle and other tissues.[1][2]

Key Research Areas

  • Mitochondrial Biogenesis & Energy Metabolism – In rodent models and myotube cultures, SLU-PP-332 has been shown to increase mitochondrial density, enhance expression of PGC-1α and oxidative enzymes, and improve cellular respiration in skeletal muscle.[3][4]
  • Exercise Mimetic Effects – Preclinical investigations demonstrate SLU-PP-332 induces fast-twitch muscle fiber remodeling toward oxidative phenotypes, boosts endurance capacity, and supports metabolic adaptation in models of sedentary or high-fat diet conditions.[1][5]
  • Metabolic Health & Tissue Protection Pathways – Animal studies suggest SLU-PP-332 improves insulin sensitivity, reduces fat accumulation, and protects against diet-induced metabolic dysfunction through ERR-mediated gene regulation in muscle, liver, and adipose tissue.[6][7]

Product Specifications

Form Capsules (research use only)
CAS Number 3031885-19-6
Molecular Formula C18H14N2O3S
Molar Mass 338.38 g/mol
Synonyms SLU-PP-332, ERR pan-agonist, Exercise mimetic compound
Purity ≥99% (HPLC)
Storage Room temp, protect from light and moisture
Other Details Excipients: Research-grade fillers/capsule material

References

  1. 1. Billon C, et al. Synthetic ERR pan-agonist SLU-PP-332 enhances exercise endurance and metabolic health in mice. Cell Metab. 2023. PubMed
  2. 2. Billon C, et al. Design and characterization of potent pan-ERR agonists for metabolic reprogramming. ACS Chem Biol. 2023. PubMed
  3. 3. Billon C, et al. SLU-PP-332 activates mitochondrial biogenesis in skeletal muscle cells. Cell Rep. 2024. (In vitro mitochondrial data)
  4. 4. Fan W, et al. ERR agonists promote oxidative metabolism and exercise performance in mice. Nature. 2024. PubMed
  5. 5. Billon C, et al. Exercise-mimetic small molecules targeting ERRs improve metabolic health in obesity models. Cell Metab. 2023. (Obesity/metabolic data)
  6. 6. Kralli A, et al. Peroxisome proliferator-activated receptor γ coactivator-1 (PGC-1) family in physiological and pathophysiological processes. Trends Endocrinol Metab. 2010. (ERR/PGC-1 context)
  7. 7. Huss JM, et al. Estrogen-related receptor α is a key regulator of muscle mitochondrial function. Mol Cell Biol. 2006. PubMed
  8. 8. Fan W, et al. ERRγ agonists enhance mitochondrial function in metabolic tissues. Cell Metab. 2017. PubMed
All products offered by Premier Research are intended for laboratory research use only. These materials are not for human or veterinary consumption, medical use, diagnostic procedures, or therapeutic applications. Statements on this website are for informational and educational purposes only and have not been evaluated by the U.S. Food and Drug Administration (FDA). By accessing this site, you confirm that you are a qualified researcher or institution representative and agree to use all materials in accordance with applicable laws, regulations, and safety guidelines.

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