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BPC-157 + TB-500 : WOLVERINE 20

BPC-157 + TB-500 : WOLVERINE 20

Original price was: $105.00.Current price is: $90.00.

BPC-157 + TB-500 : WOLVERINE BPC-157 + TB-500 blend is a research peptide combination consisting of the synthetic pentadecapeptide BPC-157 (derived from a gastric protective protein) and TB-500 (a synthetic fragment of thymosin beta-4). Preclinical studies suggest that BPC-157 promotes angiogenesis and tendon-to-bone healing, while TB-500 facilitates actin regulation, cell migration, and tissue remodeling. When…

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BPC-157 + TB-500 : WOLVERINE

BPC-157 + TB-500 blend is a research peptide combination consisting of the synthetic pentadecapeptide BPC-157 (derived from a gastric protective protein) and TB-500 (a synthetic fragment of thymosin beta-4). Preclinical studies suggest that BPC-157 promotes angiogenesis and tendon-to-bone healing, while TB-500 facilitates actin regulation, cell migration, and tissue remodeling. When studied together, these peptides may exhibit complementary actions supporting accelerated tissue repair in various injury models.[1][2]

Key Research Areas

  • Soft Tissue & Musculoskeletal Repair – In rat models of Achilles tendon transection and muscle crush injury, BPC-157 has been shown to accelerate functional recovery, enhance collagen organization, and promote tendon healing; TB-500 supports cell migration and actin sequestration in preclinical wound models.[3][4]
  • Angiogenesis & Vascularization – BPC-157 upregulates VEGF signaling and endothelial function in ischemic models, while TB-500 promotes endothelial differentiation and new vessel formation in dermal and cardiac tissues.[5][6]
  • Inflammation & Regeneration Pathways – Preclinical investigations indicate the combination may modulate inflammatory mediators, enhance fibroblast activity, and support extracellular matrix remodeling through complementary mechanisms.[1][7]

Product Specifications

CAS Number BPC-157: 137525-51-0 / TB-500: 77591-33-4
Molecular Formula Blend (BPC-157: C62H98N16O22 / TB-500: C212H350N56O78S)
Molar Mass Blend (BPC-157: 1419.56 g/mol / TB-500: 4963.50 g/mol)
Sequence BPC-157: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val

TB-500: Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser
Synonyms BPC-157/TB-500 Blend, Regeneration Blend, Wolverine Blend
Purity ≥99% (HPLC)
Form Lyophilized powder
Storage −20°C (long-term), 2–8°C (reconstituted)
Solubility Bacteriostatic water or saline for reconstitution

References

  1. 1. Chang CH, et al. The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration. J Appl Physiol. 2011. PubMed
  2. 2. Sosne G, et al. Thymosin beta 4: potential to treat corneal and dermal wounds. Ann N Y Acad Sci. 2010. PubMed
  3. 3. Staresinic M, et al. Effective therapy of transected quadriceps muscle in rat: gastric pentadecapeptide BPC 157. J Orthop Res. 2006. PubMed
  4. 4. Philp D, et al. Thymosin beta4 promotes angiogenesis, wound healing, and hair follicle development. Mech Ageing Dev. 2004. PubMed
  5. 5. Seiwerth S, et al. BPC 157 and blood vessels. Curr Pharm Des. 2014. PubMed
  6. 6. Smart N, et al. Thymosin beta4 accelerates wound healing. J Invest Dermatol. 2007. PubMed
  7. 7. Sikiric P, et al. Stable gastric pentadecapeptide BPC 157 in trials for inflammatory bowel disease. Curr Pharm Des. 2013. PubMed
All products offered by Premier Research are intended for laboratory research use only. These materials are not for human or veterinary consumption, medical use, diagnostic procedures, or therapeutic applications. Statements on this website are for informational and educational purposes only and have not been evaluated by the U.S. Food and Drug Administration (FDA). By accessing this site, you confirm that you are a qualified researcher or institution representative and agree to use all materials in accordance with applicable laws, regulations, and safety guidelines.

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