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SERMORELIN 10MG

SERMORELIN 10MG

Original price was: $85.00.Current price is: $75.00.

Sermorelin Sermorelin is a synthetic analog of growth hormone-releasing hormone (GHRH) consisting of the first 29 amino acids of native GHRH. Preclinical studies in cell cultures and animal models indicate that Sermorelin stimulates pulsatile release of endogenous growth hormone (GH) from pituitary somatotrophs, leading to increased circulating GH and IGF-1 levels without significant disruption of…

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Sermorelin

Sermorelin is a synthetic analog of growth hormone-releasing hormone (GHRH) consisting of the first 29 amino acids of native GHRH. Preclinical studies in cell cultures and animal models indicate that Sermorelin stimulates pulsatile release of endogenous growth hormone (GH) from pituitary somatotrophs, leading to increased circulating GH and IGF-1 levels without significant disruption of the natural feedback axis.[1][2]

Key Research Areas

  • Growth Hormone Secretion & Pulsatile Release – In rodent and primate models, Sermorelin has been shown to induce dose-dependent, physiological GH pulses, mimicking natural episodic secretion and supporting research into the GH axis dynamics.[3][4]
  • Metabolic & Anabolic Effects – Preclinical investigations demonstrate enhanced protein synthesis, nitrogen retention, and potential improvements in body composition in animal models of growth hormone modulation.[5][6]
  • Recovery & Tissue Maintenance Pathways – Animal studies suggest Sermorelin supports muscle repair, bone growth, and connective tissue maintenance through elevated GH/IGF-1 signaling in injury or aging models.[7][8]

Product Specifications

CAS Number 86168-78-7
Molecular Formula C149H246N44O42S
Molar Mass 3357.88 g/mol
Sequence Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2
Synonyms GHRH (1-29) NH2, Sermorelin Acetate
Purity ≥99% (HPLC)
Form Lyophilized powder
Storage −20°C (long-term), 2–8°C (reconstituted)
Solubility Bacteriostatic water or sterile saline for reconstitution

References

  1. 1. Thorner MO, et al. Growth hormone-releasing hormone: physiology and therapeutic potential. Endocr Rev. 1986. PubMed
  2. 2. Frohman LA, et al. Growth hormone-releasing hormone: synthesis, biology, and clinical implications. Endocr Rev. 1990. PubMed
  3. 3. Walker RF, et al. Pulsatile growth hormone secretion in normal young men: effects of Sermorelin. J Clin Endocrinol Metab. 1992. PubMed
  4. 4. Giustina A, et al. Sermorelin: a review of its use in the diagnosis and treatment of growth hormone deficiency. Drugs. 1996. PubMed
  5. 5. Veldhuis JD, et al. Growth hormone secretagogues: history, mechanism of action, and clinical development. Growth Horm IGF Res. 2010. PubMed
  6. 6. Sigalos JT, et al. The safety and efficacy of growth hormone secretagogues. Sex Med Rev. 2018. PubMed
  7. 7. Murphy MG, et al. Growth hormone secretagogues in aging. Endocr Rev. 2001. PubMed
  8. 8. Chapman IM, et al. Effects of growth hormone-releasing hormone on growth hormone secretion in aging. J Clin Endocrinol Metab. 1997. PubMed
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