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GHK-CU 100MG

GHK-CU 100MG

$70.00

GHK-Cu GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper Complex) is a naturally occurring tripeptide-copper complex found in human plasma, saliva, and urine. Preclinical studies in cell cultures and animal models indicate that GHK-Cu promotes collagen and glycosaminoglycan synthesis, stimulates extracellular matrix remodeling, enhances wound healing, and exhibits antioxidant and anti-inflammatory properties.[1][2] Key Research Areas Wound Healing & Tissue Remodeling…

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GHK-Cu

GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper Complex) is a naturally occurring tripeptide-copper complex found in human plasma, saliva, and urine. Preclinical studies in cell cultures and animal models indicate that GHK-Cu promotes collagen and glycosaminoglycan synthesis, stimulates extracellular matrix remodeling, enhances wound healing, and exhibits antioxidant and anti-inflammatory properties.[1][2]

Key Research Areas

  • Wound Healing & Tissue Remodeling – In vitro fibroblast cultures and animal skin wound models show GHK-Cu accelerates granulation tissue formation, increases collagen deposition, and promotes balanced matrix metalloproteinase activity for tissue repair.[3][4]
  • Antioxidant & Anti-Inflammatory Effects – Preclinical investigations demonstrate GHK-Cu reduces oxidative stress, modulates inflammatory cytokine expression, and activates protective pathways (e.g., superoxide dismutase) in models of tissue injury and aging.[5][6]
  • Cellular Regeneration & Gene Expression – Studies in human cell lines reveal GHK-Cu influences expression of genes related to tissue repair, angiogenesis, and extracellular matrix components, supporting regenerative processes in dermal and epithelial models.[1][7]

Product Specifications

CAS Number 49557-75-7
Molecular Formula C14H24CuN6O4
Molar Mass 403.92 g/mol
Sequence Gly-His-Lys-Cu2+
Synonyms Copper Tripeptide-1, GHK Copper, Copper Peptide GHK-Cu
Purity ≥99% (HPLC)
Form Lyophilized powder (blue color due to copper)
Storage −20°C (long-term), 2–8°C (reconstituted)
Solubility Bacteriostatic water or sterile saline for reconstitution

References

  1. 1. Pickart L, et al. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. Int J Mol Sci. 2018. PubMed
  2. 2. Maquart FX, et al. Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+. FEBS Lett. 1988. PubMed
  3. 3. Siméon A, et al. The tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ stimulates matrix metalloproteinase-2 expression by fibroblast cultures. Life Sci. 2000. PubMed
  4. 4. Wegrowski Y, et al. Stimulation of sulfated glycosaminoglycan synthesis by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+. Life Sci. 1992. PubMed
  5. 5. Pickart L, et al. GHK-Cu peptide in skin regeneration and anti-aging. Biogerontology. 2015. PubMed
  6. 6. Wang X, et al. GHK-Cu-liposomes accelerate scald wound healing in mice by promoting cell proliferation and angiogenesis. Wound Repair Regen. 2017. PubMed
  7. 7. Pickart L, et al. The human tripeptide GHK and tissue remodeling. J Biomol Struct Dyn. 2004. PubMed
  8. 8. Pickart L, et al. GHK and DNA: resetting the human genome to health. Biomed Res Int. 2014. PubMed
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