GUT BLEND CAPSULES – BPC-157 + GHK-CU + KPV + PEA – 500MCG/500MCG/1MG/50MCG – 60CT

GUT Blend is a research capsule formulation combining BPC-157, GHK-Cu, KPV, and PEA. Preclinical studies on the individual components suggest complementary mechanisms in gastrointestinal tissue protection, inflammation modulation, and mucosal repair. In various animal models, these compounds have been investigated for their roles in supporting gut barrier integrity, reducing inflammatory responses, and promoting healing processes.^[1]^[2]

Key Research Areas

Gastrointestinal Mucosal Protection & Healing – In rat models of gastric and intestinal injury (e.g., NSAID-induced, alcohol, or fistulas), BPC-157 has been shown to accelerate mucosal repair, stabilize gut lining, and counteract ulcer formation.^[3]^[4]
Anti-Inflammatory & Immune Modulation – Preclinical studies indicate KPV reduces pro-inflammatory cytokine expression in colonic models, while GHK-Cu and PEA modulate inflammatory pathways and support tissue homeostasis in gut injury paradigms.^[5]^[6]
Barrier Integrity & Regenerative Pathways – Animal and in vitro research suggests the components collectively promote collagen synthesis, epithelial regeneration, and balanced matrix remodeling in gastrointestinal tissue models.^[7]^[8]

Product Specifications

Form	Capsules (research use only)
Blend Composition per Capsule	BPC-157: 500 mcg GHK-Cu: 500 mcg KPV: 1 mg PEA: 50 mcg
Synonyms	GUT Blend
Storage	Cool, dry place (2–8°C recommended for long-term)
Other Details	Excipients: Research-grade fillers/capsule material

References

1. Sikiric P, et al. Stable gastric pentadecapeptide BPC 157 heals rat colovesical fistula. Eur J Pharmacol. 2016. PubMed
2. Pickart L, et al. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. Int J Mol Sci. 2018. PubMed
3. Sikiric P, et al. Pentadecapeptide BPC 157 positively affects both non-steroidal anti-inflammatory agent-induced gastrointestinal lesions and brain lesions. Life Sci. 1997. PubMed
4. Sikiric P, et al. BPC 157 and standard healing procedure. Med Sci Monit. 2013. PubMed
5. Rajora N, et al. Alpha-MSH modulates local and circulating TNF-alpha in experimental inflammatory bowel disease. J Immunol. 1997. PubMed
6. Petrella C, et al. Palmitoylethanolamide in the treatment of chronic pain caused by different etiopathogenesis. Pain Med. 2016. (PEA anti-inflammatory data)
7. Siméon A, et al. The tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ stimulates matrix metalloproteinase-2 expression by fibroblast cultures. Life Sci. 2000. PubMed
8. Sikiric P, et al. BPC 157 and blood vessels. Curr Pharm Des. 2014. PubMed

All products offered by Premier Research are intended for laboratory research use only. These materials are not for human or veterinary consumption, medical use, diagnostic procedures, or therapeutic applications. Statements on this website are for informational and educational purposes only and have not been evaluated by the U.S. Food and Drug Administration (FDA). By accessing this site, you confirm that you are a qualified researcher or institution representative and agree to use all materials in accordance with applicable laws, regulations, and safety guidelines.