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METHYLENE BLUE 10MG – 60CT
METHYLENE BLUE CAPSULES 10MG – 60CT Methylene Blue is a synthetic phenothiazine dye and redox-active compound. Preclinical studies in cell cultures and animal models indicate that Methylene Blue acts as an electron carrier in the mitochondrial electron transport chain, enhances cellular respiration, reduces oxidative stress, and exhibits neuroprotective effects by improving mitochondrial function and inhibiting…
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METHYLENE BLUE CAPSULES 10MG – 60CT
Methylene Blue is a synthetic phenothiazine dye and redox-active compound. Preclinical studies in cell cultures and animal models indicate that Methylene Blue acts as an electron carrier in the mitochondrial electron transport chain, enhances cellular respiration, reduces oxidative stress, and exhibits neuroprotective effects by improving mitochondrial function and inhibiting tau aggregation.[1][2]
Key Research Areas
- Mitochondrial Function & Energy Metabolism – In neuronal cell cultures and rodent models of neurodegeneration, Methylene Blue has been shown to bypass blocked electron transport complexes, increase ATP production, and enhance oxygen consumption rates.[3][4]
- Neuroprotection & Cognitive Support – Preclinical investigations demonstrate Methylene Blue reduces amyloid-beta toxicity, inhibits tau protein aggregation, and improves memory performance in models of Alzheimer’s disease and traumatic brain injury.[5][6]
- Antioxidant & Anti-Inflammatory Pathways – Animal studies suggest Methylene Blue scavenges reactive oxygen species, modulates inflammatory responses, and protects against oxidative damage in models of ischemia, sepsis, and aging.[7][8]
Product Specifications
| Form | Capsules (research use only) |
| CAS Number | 61-73-4 |
| Molecular Formula | C16H18ClN3S |
| Molar Mass | 319.85 g/mol |
| Synonyms | Methylene Blue Chloride, Methylthioninium chloride |
| Purity | ≥99% (HPLC) |
| Storage | Room temp |
| Other Details | Excipients: Research-grade fillers/capsule material |
References
- 1. Rojas JC, et al. Neurometabolic mechanisms for memory enhancement and neuroprotection of methylene blue. Prog Neurobiol. 2012. PubMed
- 2. Atamna H, et al. Methylene blue delays cellular senescence and enhances key mitochondrial biochemical pathways. FASEB J. 2008. PubMed
- 3. Wen Y, et al. Methylene blue provides behavioral and metabolic neuroprotection against optic nerve crush injury. Neurobiol Dis. 2016. PubMed
- 4. Tucker LD, et al. Methylene blue treatment reverses spatial memory deficits in a mouse model of Alzheimer’s disease. Neurobiol Aging. 2011. PubMed
- 5. Medina DX, et al. Methylene blue reduces Aβ levels and rescues early cognitive deficit by increasing proteasome activity in 3xTg-AD mice. Brain Res. 2011. PubMed
- 6. Stack C, et al. Methylene blue upregulates BDNF and PGC-1α in a triple transgenic mouse model of Alzheimer’s disease. J Alzheimers Dis. 2014. PubMed
- 7. Poteet E, et al. Neuroprotective actions of methylene blue in ischemic stroke. Brain Res. 2013. PubMed
- 8. Shen Q, et al. Methylene blue attenuates cerebral ischemia-reperfusion injury in rats. Neurosci Lett. 2017. PubMed





