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CARDARINE (GW501516) 10MG - 60CT

CARDARINE (GW501516) 10MG – 60CT

$70.00

CARDARINE (GW501516) CAPSULES 10MG – 60CT Cardarine (GW501516) is a synthetic small-molecule PPARδ (peroxisome proliferator-activated receptor delta) agonist. Preclinical studies in cell cultures and animal models indicate that GW501516 activates PPARδ, upregulates genes involved in fatty acid oxidation and mitochondrial biogenesis, and enhances endurance capacity and metabolic flexibility.[1][2] Key Research Areas Fatty Acid Oxidation &…

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CARDARINE (GW501516) CAPSULES 10MG – 60CT

Cardarine (GW501516) is a synthetic small-molecule PPARδ (peroxisome proliferator-activated receptor delta) agonist. Preclinical studies in cell cultures and animal models indicate that GW501516 activates PPARδ, upregulates genes involved in fatty acid oxidation and mitochondrial biogenesis, and enhances endurance capacity and metabolic flexibility.[1][2]

Key Research Areas

  • Fatty Acid Oxidation & Energy Metabolism – In rodent models of obesity and metabolic syndrome, GW501516 has been shown to increase fatty acid β-oxidation in skeletal muscle, reduce adiposity, and improve lipid profiles without altering food intake.[3][4]
  • Exercise Performance & Endurance Enhancement – Preclinical investigations demonstrate GW501516 induces a shift toward oxidative muscle fibers, boosts running endurance, and mimics some molecular adaptations of physical exercise in sedentary animal models.[5][6]
  • Cardiovascular & Anti-Inflammatory Pathways – Animal studies suggest GW501516 protects against vascular inflammation, improves endothelial function, and reduces atherosclerotic lesion formation in models of cardiovascular disease.[7][8]

Product Specifications

Form Capsules (research use only)
CAS Number 317318-70-0
Molecular Formula C21H18F3NO3S2
Molar Mass 453.50 g/mol
Synonyms GW501516, Cardarine, PPARδ agonist
Purity ≥99% (HPLC)
Storage Room temp, protect from light and moisture
Other Details Excipients: Research-grade fillers/capsule material

References

  1. 1. Oliver WR Jr, et al. A selective peroxisome proliferator-activated receptor δ agonist promotes reverse cholesterol transport. Proc Natl Acad Sci U S A. 2001. PubMed
  2. 2. Wang YX, et al. Regulation of muscle fiber type and running endurance by PPARδ. PLoS Biol. 2004. PubMed
  3. 3. Tanaka T, et al. Activation of PPARδ promotes reversal of metabolic syndrome. Proc Natl Acad Sci U S A. 2003. PubMed
  4. 4. Sprecher DL, et al. Effects of PPARδ agonist GW501516 on lipid metabolism in insulin-resistant rhesus monkeys. Arterioscler Thromb Vasc Biol. 2007. PubMed
  5. 5. Narkar VA, et al. AMPK and PPARδ agonists are exercise mimetics. Cell. 2008. PubMed
  6. 6. Jäger S, et al. PPARδ agonism increases endurance performance in mice. Cell Metab. 2008. PubMed
  7. 7. Barish GD, et al. PPARδ: a dagger in the heart of the metabolic syndrome. J Clin Invest. 2006. PubMed
  8. 8. Cheang WS, et al. GW501516 activates PPARδ to reduce atherosclerosis in mice. Arterioscler Thromb Vasc Biol. 2008. PubMed
All products offered by Premier Research are intended for laboratory research use only. These materials are not for human or veterinary consumption, medical use, diagnostic procedures, or therapeutic applications. Statements on this website are for informational and educational purposes only and have not been evaluated by the U.S. Food and Drug Administration (FDA). By accessing this site, you confirm that you are a qualified researcher or institution representative and agree to use all materials in accordance with applicable laws, regulations, and safety guidelines.

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